Clinical Research Directory

Inclusion Criteria: * Male or female subjects aged≥18years and≤75 years at the time of signing the Informed Consent Form (ICF). * At screening, Body Mass Index (BMI)≥28kg/m² * Weight change due to diet and exercise alone within 3 months prior to screening did not exceed 5%. Exclusion Criteria: * Previously diagnosed obesity caused by monogenic mutations, other diseases, or medications. * Previous diagnosis of diabetes; or HbA1c ≥ 6.5% or fasting blood glucose ≥ 7.0 mmol/L at screening. * Used of medicines or treatments that affect weight within 3 months prior to screening. * History of acute or chronic pancreatitis, or pancreatic injury. * History of medullary thyroid carcinoma (MTC) or type 2 multiple endocrine neoplasia (MEN2) in personal or family history. * History of medullary thyroid carcinoma (MTC) or type 2 multiple endocrine neoplasia (MEN2) in personal or family history. * Patient Health Questionnaire-9 (PHQ-9) scale score is ≥ 15 at screening * Screening Columbia-Suicide Severity Rating Scale(C-SSRS) questionnaire suicide ideation response of "Category 4 or 5," or any "yes" response to suicidal behavior questions