Clinical Research Directory

Inclusion Criteria: * Be aged 18-55 years * Willing and have capacity to provide written informed consent * Healthy adult volunteers classified as ASA 1 * Non-smoker (this does not exclude vaping) * Willing and able to comply with study procedures and duration Exclusion Criteria: * History of Bleomycin treatment at any time * Smokers or individuals exposed to high levels of carbon monoxide * Compromised circulation, injury, or physical malfunction of the sensor sites which would limit the ability to test sites needed for the study * Morbidly obese (defined as BMI \>39.5) or significantly underweight (BMI \<18) * Pregnancy * Participants who can conceive a pregnancy or carry a child (including women, trans men and non-binary people) will be required to demonstrate a negative pregnancy test * Unwillingness or inability to remove coloured nail polish or nail attachments from test digits (relevant for reference pulse oximeter) or to have medical monitoring attached * Known health conditions or medications disclosed on Health Assessment Form which mean that participant is not healthy * Allergy to lidocaine * Known allergy to adhesives used in medical dressings or tapes or materials used to adhere NeWTS components. * Enrolment in any other clinical investigation/trial that is deemed would compromise the validity of the data or safety of the patient (at the discretion of the local PI) * Sunburn/spray tan or other pigments on hands