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Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia
Sponsor: New York Medical College
Summary
The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to block these channels from causing VT with targeted radiofrequency ablation (cautery). Participants undergoing VT ablation mapping of these channels by pacing many sites within the scar area and determining where these channels exit the scar into normal tissue. These exits will be ablated. Immediate success and success at 1 year will be evaluated.
Official title: Segmental Substrate Isolation for the Treatment of Ventricular Tachycardia in Patients With Structural Heart Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2025-03-27
Completion Date
2028-12-09
Last Updated
2026-09-10
Healthy Volunteers
No
Interventions
Selective Substrate Isolation
Ablation will be guided by mapping the substrate "from the inside out" by identifying conducting channels as they might be activated during VT. Extensive pace mapping will be performed within scar areas identified during sinus rhythm mapping. The course of these channels will be identified and ablated across the distal portion, just proximal to the exit based on shortest stimulus-to-QRS interval obtained.
Locations (1)
Westchester Medical Center
Valhalla, New York, United States