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Steroids in the Treatment of Deep Neck Space Infections
Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital
Summary
This randomized, double-blind, placebo-controlled clinical trial evaluated the efficacy and safety of dexamethasone as an adjunct to standard treatment in patients with deep neck infections. Participants were randomly assigned to receive either a single intravenous dose of 8 mg dexamethasone or placebo in addition to standard treatment. The study evaluated changes in pain severity, interincisor distance, and body temperature, as well as the time to pain-free swallowing. Participants were followed from baseline through Day 7.
Official title: Efficacy and Safety of Steroids in the Treatment of Deep Neck Space Infections: A Double-Blind, Randomized, Placebo-Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2025-03-26
Completion Date
2026-06-05
Last Updated
2026-09-11
Healthy Volunteers
No
Conditions
Interventions
Dexamethasone (IV)
Dexamethasone 8 mg was administered intravenously as a single dose in addition to standard treatment for deep neck infection.
Normal Saline
Normal saline (2 mL) was administered intravenously as a single dose as placebo in addition to standard treatment for deep neck infection.
Locations (1)
Kartal Dr. Lutfi Kirdar City Hospital
Istanbul, Istanbul, Turkey (Türkiye)