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NCT07815093

Multimodal Artificial Intelligence for Non-Invasive Colorectal Cancer Screening Based on Holographic Biology

Sponsor: Xiuli Zuo

View on ClinicalTrials.gov

Summary

The purpose of this study is to propose a non-invasive screening method by integrating holographic biological theory and artificial intelligence technology. A colorectal cancer risk assessment model will be constructed by analyzing multimodal data including facial features, tongue image characteristics and exhaled gas. The hypothesis of this study is that the model can attain both sensitivity and specificity of 80%.This study will enroll patients aged 18-80 years scheduled to undergo colonoscopy. All participants shall provide informed consent and sign the informed consent form. Patients will be excluded if they have severe cardiac, cerebral, pulmonary or renal dysfunction, or psychiatric disorders precluding colonoscopy, have a history of gastrointestinal surgery, or have taken bismuth agents or other staining medications. Based on estimates from existing literature, the training set will require tongue images, facial images, exhaled gas analysis results and colonoscopic diagnoses from 5000 patients, and the test set will require such data from 6000 patients.

Official title: Multimodal Artificial Intelligence for Non-Invasive Colorectal Cancer Screening Based on Holographic Biology.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

11000

Start Date

2026-10-01

Completion Date

2028-07-01

Last Updated

2026-09-11

Healthy Volunteers

Not specified

Interventions

OTHER

Multimodal non-invasive detection for colorectal cancer

Collection of facial images, tongue images and exhaled gas data from participants. No therapeutic intervention is performed. The collected multimodal data will be used to build an artificial intelligence-based colorectal cancer risk assessment model.