Clinical Research Directory

Inclusion Criteria: 1. Age 65 years and older. 2. Intact consciousness and cognitive ability to understand and cooperate with the study protocol. 3. Capable of oral ingestion and self-administration of the study formula/placebo. 4. Meets at least one of the following priority recruitment criteria: 1. Screened positive for decline in at least one WHO ICOPE intrinsic capacity domain (locomotion, vitality, cognition, psychology, vision, or hearing). 2. Sarcopenia risk based on AWGS 2019 criteria: low handgrip strength (\<28 kg for men; \<18 kg for women), slow 6-meter gait speed (\<1.0 m/s), or Short Physical Performance Battery (SPPB) score ≤ 9. 5. Ability to attend scheduled hospital outpatient visits at baseline (Week 0) and Week 12. 6. Willing and able to provide written informed consent. Exclusion Criteria: 1. Severe hepatic impairment (GPT/ALT \> 3 times the upper limit of normal, or a confirmed diagnosis of liver cirrhosis). 2. Severe renal impairment (serum creatinine ≥ 2.0 mg/dL, eGFR \< 30 mL/min/1.73m², or a confirmed history of renal failure, chronic kidney disease, uremia, or dialysis). 3. Confirmed clinical diagnosis of dementia. 4. Active malignant neoplasms currently undergoing active oncological therapy (chemotherapy, radiotherapy, or targeted therapy). 5. Current use of oral anticoagulant medication (Warfarin) due to potential interactions with fish oil and vitamin K2. 6. Known allergy or hypersensitivity to any ingredient of the study product (dairy, soy, or fish sources). 7. High-dose supplementation with whey protein, fish oil, or botanical extracts within the past 3 months. 8. Presence of an active middle-ear implant or cochlear implant (to eliminate confounding factors during hearing assessments).