Clinical Research Directory
Browse clinical research sites, groups, and studies.
Speech Therapy for Children With Rare Genetic Conditions and Childhood Apraxia of Speech
Sponsor: Murdoch Childrens Research Institute
Summary
The goal of this trial is to learn if speech therapy can improve speech accuracy in children with rare genetic conditions and childhood apraxia of speech (CAS). This study will look at each child individually. Participants will complete 4-weeks of motor speech therapy (3 times per week) and will complete speech assessments before, during and after therapy to measure change. The motor speech therapy will be either Rapid Syllable Transition Treatment (ReST) or Dynamic Temporal and Tactile Cueing (DTTC). Assignment to ReST or DTTC will be based on the participant's age and speech ability. This trial will not compare ReST and DTTC.
Official title: A Single Case Experimental Design Study of Motor Speech Treatment for Children With Childhood Apraxia of Speech and Rare Genetic Conditions
Key Details
Gender
All
Age Range
3 Years - 16 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-07-01
Completion Date
2028-12
Last Updated
2026-09-11
Healthy Volunteers
No
Interventions
Rapid Syllable Transition Treatment
ReST is a motor speech treatment targeting prosodic accuracy (correct stress patterns) and smooth transitions between sounds. It uses pseudo-words (also known as nonwords) to remove reliance on meaning and focus on pure motor planning and programming demands (i.e., the core deficit in CAS). Participants will complete 60 minutes of motor speech therapy (ReST), 3 times per week for 4 weeks, totalling 12 treatment sessions.
Dynamic Temporal and Tactile Cueing
DTTC is a motor speech treatment. It is designed to support children with CAS who require intensive modelling, cueing, and motor practice. The treatment focuses on syllables rather than isolated sounds and progresses through a hierarchy of simultaneous production (i.e., with the clinician), immediate (copying), delayed, and spontaneous productions based on performance. Cueing is highly flexible and dynamic to ensure accurate speech movement patterns before practice intensity increases. Participants will complete 60 minutes of motor speech therapy (DTTC), 3 times per week for 4 weeks, totalling 12 treatment sessions.
Locations (1)
Murdoch Children's Research Institute
Melbourne, Victoria, Australia