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Standard Versus Double Alpha Blockers Treatment for Symptomatic Benign Prostatic Obstruction
Sponsor: Mansoura University
Summary
Failed medical treatment to alleviate LUTS and AUR is an indication for intervention, some trials were published elucidating the possible use of standard dose tamsulosin and silodosin and double dose tamsulosin but to the best of our knowledge, no studies with head-to-head comparison between Tamsulosin and Combination of Tamsulosin and Silodosin for Management of Lower Urinary Tract Symptoms and Acute Urine Retention in Patients with Benign Prostatic Hyperplasia.
Official title: Standard Versus Double Alpha Blockers Treatment for Symptomatic Benign Prostatic Obstruction: A Randomized Clinical Trial
Key Details
Gender
MALE
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
140
Start Date
2025-10-12
Completion Date
2026-11
Last Updated
2026-09-11
Healthy Volunteers
No
Conditions
Interventions
alpha blocker monotherapy Tamsulosin
Effect of Tamsulosin and placebo in Management of Lower Urinary Tract Symptoms and Acute Urine Retention in Patients with Benign Prostatic Hyperplasia.
alpha blockers Tamsulosin and Silodosin
BPH patients are given dual alpha blockers compared to single alpha blocker drug
Locations (1)
Urology and Nephrology Center, Mnasoura University
Al Mansurah, Dakahlia Governorate, Egypt