Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Oral Fruit Concentrate Supplementation in Pre-Metabolic Syndrome.
Sponsor: University of Central Lancashire
Summary
Cardiovascular disease, type 2 diabetes mellitus and associated metabolic diseases are leading causes of morbidity and mortality worldwide; therefore, effective preventive interventions are required. Pre-metabolic syndrome, characterised by the presence of two metabolic syndrome components, represents an important opportunity for intervention before progression to metabolic syndrome and overt cardiometabolic disease. Dietary interventions are particularly sought after because they generally carry less risk than pharmacological treatments. Anthocyanins, found in high concentrations in tart cherries and blueberries, possess antioxidant and anti-inflammatory properties that may improve cardiometabolic health. However, the cardiometabolic effects of tart cherry and blueberry supplementation have not been directly compared in individuals with pre-metabolic syndrome. Therefore, the primary purpose of the proposed investigation is to compare the ability of oral tart cherry and blueberry supplementation to improve cardiometabolic parameters in individuals with pre-metabolic syndrome.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2021-05-01
Completion Date
2026-09-01
Last Updated
2026-09-11
Healthy Volunteers
No
Conditions
Interventions
Blueberry
30 mL of blueberry juice concentrate, which will be diluted with 100 mL of water - taken twice per day.
Cherry
30 mL of tart juice concentrate, which will be diluted with 100 mL of water - taken twice per day.
Placebo
Identical in taste and colour to the supplement juice, but with no anthocyanin content.
Locations (1)
University of Central Lancashire
Preston, United Kingdom