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RECRUITING
NCT07816809
NA

Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

Sponsor: Colorado State University

View on ClinicalTrials.gov

Summary

Bacteriophages are viruses that can selectively infect specific species and strains of bacteria. Some bacterial species in the human gut have been negatively associated with gut health and skin health. This study is designed to measure the efficacy of two different bacteriophage-based treatments for 4 weeks to improve gut and skin health. These treatments are bacteriophage that target specific strains of Escherichia coli and Staphylococcus Aureus.

Official title: Phage-CLEAR: Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2026-09-14

Completion Date

2028-01

Last Updated

2026-09-14

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Bacteriophages - MuniPhage

1 x 106 Plaque Forming Units (PFU) of bacteriophage strains PBH34, CAH57, BFX121, and DNK95

DIETARY_SUPPLEMENT

Bacteriophages - RenuPhage

1 x 106 PFU of phage strains LG91, BD117, CD007, and PD23

OTHER

Placebo

Rice maltodextrin

Locations (1)

Colorado State University

Fort Collins, Colorado, United States