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Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience
Sponsor: Colorado State University
Summary
Bacteriophages are viruses that can selectively infect specific species and strains of bacteria. Some bacterial species in the human gut have been negatively associated with gut health and skin health. This study is designed to measure the efficacy of two different bacteriophage-based treatments for 4 weeks to improve gut and skin health. These treatments are bacteriophage that target specific strains of Escherichia coli and Staphylococcus Aureus.
Official title: Phage-CLEAR: Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-09-14
Completion Date
2028-01
Last Updated
2026-09-14
Healthy Volunteers
Yes
Conditions
Interventions
Bacteriophages - MuniPhage
1 x 106 Plaque Forming Units (PFU) of bacteriophage strains PBH34, CAH57, BFX121, and DNK95
Bacteriophages - RenuPhage
1 x 106 PFU of phage strains LG91, BD117, CD007, and PD23
Placebo
Rice maltodextrin
Locations (1)
Colorado State University
Fort Collins, Colorado, United States