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COMPLETED
NCT07817420
NA

Effect of Adding Silicon Dioxide (SiO₂) Nanoparticles to a Printable Acrylic Resin Denture Base

Sponsor: Mansoura University

View on ClinicalTrials.gov

Summary

This clinical study evaluated whether adding a small amount (0.5 wt%) of silicon dioxide (SiO₂) nanoparticles to a 3D-printable acrylic denture material could improve the clinical performance of implant-retained mandibular overdentures. the results showed that the SiO₂-modified denture bases had smoother surfaces and were associated with better peri-implant soft tissue measurements than the conventional 3D-printed denture bases. The modified denture bases also showed lower bacterial counts and reduced Candida albicans levels during follow-up. No implant failures were reported during the study period.

Official title: Effect of Adding Silicon Dioxide (SiO₂) Nanoparticles to a Printable Acrylic Resin Denture Base Material for Implant Overdentures: A Clinical Comparative Study

Key Details

Gender

All

Age Range

50 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2023-02-01

Completion Date

2025-09-10

Last Updated

2026-09-14

Healthy Volunteers

No

Interventions

DEVICE

Standard 3D-printed acrylic resin denture base

Fabrication of mandibular overdentures using standard 3D-printable acrylic resin without any nanoparticle modification. The dentures are retained by two bilateral mandibular implants with ball attachments.

DEVICE

SIO2 nanoparticle-modified 3D-printed acrylic resin denture base

Fabrication of mandibular overdentures using 3D-printable acrylic resin incorporated with $0.5 wt% silanized SIO2 nanoparticles (homogenized using a high-speed homogenizer). The dentures are retained by two bilateral mandibular implants with ball attachments.

Locations (1)

Mansoura university faculty of dentistry

Al Mansurah, Egypt