Clinical Research Directory

Inclusion Criteria: * Clinical diagnosis of interstitial lung disease * Radiologic lung abnormalities on diagnostic CT chest * Anatomic imaging (clinical diagnostic CT chest) obtained within ≤ 180 days prior to the planned FAPI 46 imaging exam or within 14 days after the imaging exam. * Willingness and ability to provide informed consent Exclusion Criteria: * Pregnant as determined by a pregnancy test as per institutional guidelines for individuals of child-bearing potential * Declining to use effective contraceptive methods during the study (for individuals of child-producing potential) * Need for emergent surgery that would be delayed by participation * Bacterial, viral, or fungal infections requiring systemic therapy * Serious co-morbidities and serious nonmalignant disease (e.g., hydronephrosis, kidney failure, liver failure, or other conditions) that in the opinion of the investigator, physician of record and/or Sofie could compromise patient safety and/or protocol objectives. * No available chest CT radiological data * No clear diagnosis of ILD * Intolerability to perform the exam due to exuberant dyspnea or severely low pulmonary capacity. * Breastfeeding. Note: nursing parents are allowed if the potential participant commits to pumping breast milk and discarding it from injection to ≥ 24 hours from the time of the \[68Ga\]FAPI-46 injection. * Known hypersensitivity to any excipients used in \[68Ga\]FAPI-46