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A Trial in Healthy Participants to Assess Drug Interaction Potential of BGB-43395
Sponsor: BeOne Medicines
Summary
This study will enroll healthy participants to evaluate whether BGB-43395 interacts with other drugs, including midazolam, celecoxib, dabigatran, and rosuvastatin.
Official title: A Phase 1, Open-label, Fixed-sequence Trial in Healthy Participants to Assess the Drug Interaction Potential of BGB-43395 With A Drug Cocktail Representative for CYP3A4, CYP2C9, P-gp, and BCRP Substrates
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2026-09-25
Completion Date
2026-11-22
Last Updated
2026-10-08
Healthy Volunteers
Yes
Conditions
Interventions
BGB-43395
Administered orally
Midazolam
Administered orally
Celecoxib
Administered orally
Dabigatran etexilate
Administered orally
Rosuvastatin
Administered orally
Locations (1)
Fortrea CRU
Dallas, Texas, United States