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Post-op Analgesia of Nail Unit Procedures
Sponsor: University of Miami
Summary
The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen/ibuprofen in controlling post-operative pain after the following nail unit procedures.
Official title: Post-operative Analgesia of Nail Unit Procedures: A Prospective Pilot Study Comparing Suzetrigine vs. Oxycodone+Acetaminophen vs. Acetaminophen/Ibuprofen
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2026-10-01
Completion Date
2028-10-01
Last Updated
2026-10-01
Healthy Volunteers
No
Conditions
Interventions
Suzetrigine
Participants will receive two 50 mg oral tablets on day 1, followed by 50 mg oral tablets every 12 hours for 5 days
Oxycodone/Acetaminophen
Participants will receive oral oxycodone 5 mg/acetaminophen 325 mg (Percocet®) as a fixed-dose combination tablet every 6 hours for 5 days, beginning on the day of the nail procedure.
Acetaminophen
Participants will receive acetaminophen 650 mg orally every 6 hours, alternating with ibuprofen, for 5 days beginning on the day of the nail procedure.
Ibuprofen
Participants will receive ibuprofen 400 mg orally every 6 hours, alternating with acetaminophen, for 5 days beginning on the day of the nail procedure.
Locations (1)
University of Miami, Phillip Frost Dermatology Clinic
Miami, Florida, United States