Clinical Research Directory
Browse clinical research sites, groups, and studies.
MDW as a Novel Diagnostic Biomarker in LONS Among Preterm Neonates
Sponsor: Tanta University
Summary
This study aims to evaluate the diagnostic accuracy of monocyte distribution width (MDW) as a novel biomarker for late-onset neonatal sepsis in preterm neonates and to assess its association with disease severity and short-term clinical outcomes
Official title: Monocyte Distribution Width as a Novel Diagnostic Biomarker in Late-Onset Sepsis Among Preterm Neonates
Key Details
Gender
All
Age Range
73 Hours - 28 Days
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2026-07-01
Completion Date
2027-07-30
Last Updated
2026-09-15
Healthy Volunteers
Not specified
Conditions
Interventions
MDW measurement
Monocyte Distribution Width (MDW), which represents the standard deviation of monocyte cell volume, will be measured at the time of first clinical suspicion of LONS, preferably before the initiation of antibiotic therapy when possible, using 2 mL peripheral venous blood collected in EDTA tubes. Blood samples will be analyzed as soon as possible after collection using an automated hematology analyzer that reports MDW. The result will be recorded as part of the CBC without requiring an additional blood sample.
Locations (1)
Faculty of Medicine, Tanta University
Tanta, Egypt