Clinical Research Directory

Inclusion Criteria: * Women must be postmenopausal. * History of angina, ischemic symptoms, or symptoms consistent with ischemia in the absence of obstructive coronary artery disease. * No obstructive coronary artery disease (\<50% stenosis in any epicardial coronary artery or fractional flow reserve \>0.80). * Clinically documented coronary microvascular dysfunction (CMD), including coronary flow reserve \<2.5 and/or index of microcirculatory resistance ≥25, or equivalent documentation in the medical record. * Stable cardiometabolic medication regimen for at least 2 months before enrollment. * Willingness to consume the study-provided plant-based diet and complete all study procedures. * Ability to provide informed consent Exclusion: * Obstructive coronary artery disease or prior coronary revascularization (PCI or CABG). * Recent acute coronary syndrome, unstable angina, decompensated heart failure, or other clinically unstable cardiovascular disease. * Significant structural heart disease, uncontrolled arrhythmia, severe uncontrolled hypertension, or symptomatic hypotension. * Severe renal disease (eGFR \<30 mL/min/1.73 m²) or significant liver disease. * Current vegetarian or vegan diet, or habitual consumption of ≤4 servings of animal products per week. * Severe food allergies, dietary restrictions, or gastrointestinal conditions that would prevent adherence to the study diet. * Current use of weight-loss medications, including GLP-1 receptor agonists. * Active eating disorder. * Recent (\>5%) intentional or unintentional weight change within the previous 3 months. * Participation in another interventional study that could affect study outcomes. * Any medical, psychiatric, or social condition that, in the investigator's judgment, would make participation unsafe or interfere with study completion.