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Possible Association Between Behçet's Disease and Periodontal Diseases
Sponsor: Gazi University
Summary
Aim: This study explores the connection between Behçet's disease (BD), characterized by persistent oral and genital ulcers alongside iritis, and periodontal disease. It examines the levels of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and nitric oxide (NO) in gingival crevicular fluid (GCF) and saliva. Methods: Forty Behçet's patients with gingivitis or periodontitis and 47 patients with either gingivitis or periodontitis but without BD were studied. Periodontal status was recorded with standard clinical indexes. GCF and saliva samples were obtained. NO, IL-1β and TNF-α levels were analysed. Current Behçet's symptoms and medications usage were recorded.
Key Details
Gender
All
Age Range
21 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
87
Start Date
2016-02-16
Completion Date
2019-02-18
Last Updated
2026-09-16
Healthy Volunteers
No
Interventions
Periodontal clinical indexes, saliva, gingival crevicular fluid sampling