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Laparoscopic vs Open Appendectomy in Obese Patients
Sponsor: University of Health Sciences Lahore
Summary
Acute appendicitis is one of the most common surgical emergencies globally. While surgical removal of the appendix (appendectomy) is the definitive treatment, the optimal surgical approach-laparoscopic versus open-remains widely debated, particularly in obese patients. Obese individuals present unique surgical challenges due to increased abdominal wall thickness, which often necessitates larger skin incisions during open procedures, potentially increasing postoperative pain, wound healing times, and wound complications. This study aims to compare the postoperative outcomes of laparoscopic appendectomy versus standard open appendectomy in obese patients (BMI ≥ 30 kg/m²) presenting with acute appendicitis. Participants will be randomly assigned to undergo either open appendectomy or laparoscopic appendectomy. The primary outcomes evaluated will be the incidence of surgical site infections (including superficial wound infections and intra-abdominal abscesses) up to 30 days post-procedure and the total length of hospital stay (in days).
Official title: Evaluation of Post Operative Outcomes of Laparoscopic and Open Appendectomy in Obese Patients
Key Details
Gender
All
Age Range
15 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
166
Start Date
2026-10-02
Completion Date
2027-04-30
Last Updated
2026-09-16
Healthy Volunteers
No
Interventions
Open Appendectomy
Open surgical removal of the appendix performed via a standard grid-iron incision under general anesthesia with standard prophylactic antibiotics.
Laparoscopic Appendectomy
Laparoscopic surgical removal of the appendix using a standard 3-port configuration (umbilical, left iliac fossa, and lower midline ports) under general anesthesia with standard prophylactic antibiotics.