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Inter-Limb Transfer in Acute Stroke
Sponsor: University Hospital of Mont-Godinne
Summary
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to identify the neural substrates underlying this inter-limb transfer. To achieve this, healthy individuals, acute and chronic stroke patients will perform proximal and distal MSkL tasks using serious games implemented on robotic devices. This will be complemented by behavioural assessments and multimodal MRI.
Official title: Identifying Brain Regions Critical for Human Motor Learning Through Anatomic-functional Correlations of Deficits in Acute Stroke: Integrated Robotic and Voxel-based Lesion Symptom Mapping Approach
Key Details
Gender
All
Age Range
40 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2026-08-11
Completion Date
2032-01
Last Updated
2026-09-16
Healthy Volunteers
Yes
Interventions
REAplan®
motor skill learning with the REAplan® rehabilitation robot, to be performed with ipsilesional arm
Dextrain Manipulandum®
motor skill learning with the Dextrain Manipulandum® dexterity tool to be performed with ipsilesional hand
REAplan®
proximal motor control and motor skill assessement with the REAplan® rehabilitation robot, to be performed by each arm
Dextrain Manipulandum®
distal motor skill assessment with the Dextrain Manipulandum® dexterity tool to be performed by each hand
Locations (2)
CHU UCL Namur
Yvoir, Namur, Belgium
Cliniques universitaires Saint-Luc
Brussels, Belgium