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NCT07823426

Cervical Spinal Cord Signal Abnormalities in Patients With Cervical Radicular Pain

Sponsor: Ankara City Hospital Bilkent

View on ClinicalTrials.gov

Summary

This prospective observational study aims to determine the prevalence of cervical spinal cord signal abnormalities, including myelomalacia, among adult patients presenting to a tertiary pain clinic with cervical radicular pain. A total of 400 consecutive patients will be enrolled. Clinical and neurological examination findings, including the Hoffmann sign and other findings suggestive of cervical spinal cord involvement, will be recorded together with cervical magnetic resonance imaging (MRI) findings obtained as part of routine clinical care. The primary outcome is the prevalence of cervical spinal cord signal abnormalities, including myelomalacia, on cervical MRI. Secondary outcomes include the treatment strategy selected during routine clinical care, clinical and radiological factors associated with treatment selection, the relationship between the Hoffmann sign and cervical spinal cord abnormalities, and referral for surgical evaluation. This is an observational study. Participation in the study will not determine or alter diagnostic or treatment decisions, which will be made by the treating physician according to routine clinical practice.

Official title: Prevalence of Cervical Spinal Cord Signal Abnormalities and Determinants of Treatment Selection in Patients With Cervical Radicular Pain: A Prospective Cohort Study

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2026-10-01

Completion Date

2027-03-31

Last Updated

2026-09-16

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Clinical and Cervical MRI Assessment

Participants will undergo routine clinical and neurological evaluation, including assessment of the Hoffmann sign and other neurological findings, together with evaluation of cervical magnetic resonance imaging (MRI) findings. Cervical MRI findings, including spinal canal stenosis, spinal cord compression, intramedullary signal abnormalities, and myelomalacia, will be recorded. All assessments are performed as part of routine clinical care. No diagnostic procedure or treatment is assigned by the study protocol.

Locations (1)

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)