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Post-Vasectomy Pain RCT
Sponsor: Columbia University
Summary
This is a prospective four-armed unblinded randomized controlled trial to assess four different potential post-operative treatment options for men who undergo a vasectomy. The aims of this study are: * To determine whether the addition of nonsteroidal anti-inflammatory drugs (NSAIDs) to acetaminophen results in improved pain after vasectomy; * To determine whether the addition of opioid pain medication to acetaminophen and/or NSAIDs results in improved pain after vasectomy; * To determine whether the use of NSAIDs for post-operative pain management increases risk of hematoma after vasectomy.
Official title: A Randomized Controlled Trial of Post-vasectomy Pain Management
Key Details
Gender
MALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-09-10
Completion Date
2035-12-31
Last Updated
2026-09-17
Healthy Volunteers
No
Conditions
Interventions
Acetaminophen
Acetaminophen is a widely used, over-the-counter medication that relieves mild to moderate pain and reduces fever. Unlike NSAIDs like ibuprofen, it does not treat inflammation or swelling.
ibuprofen
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate pain, reduce fever, and decrease inflammation.
oxycodone
Oxycodone is a potent semi-synthetic opioid analgesic used to treat moderate to severe pain when other treatments are insufficient
Locations (2)
Columbia University Medical Center/ New York Presbyterian Hospital
New York, New York, United States
New York-Presbyterian The One
White Plains, New York, United States