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Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
Sponsor: University of Barcelona
Summary
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash). Following a baseline oral health assessment, participants will use the assigned mouthwash twice daily for 4 consecutive days while refraining from all mechanical oral hygiene practices (e.g., tooth brushing). The trial follows a 2-phase crossover design, where participants use one mouthwash in the first phase and the other in the second phase, separated by a 15-day washout period.
Official title: Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash: a Randomized, Double-blind, Controlled, Crossover Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2026-03-02
Completion Date
2026-07-13
Last Updated
2026-09-17
Healthy Volunteers
Yes
Interventions
Bioflavonoid mouthwash
Rinsed twice daily for 4 consecutive days. Abstinence from mechanical oral hygiene during use. 15-day washout before/after sequence.
Chlorhexidine 0.12% mouthwash
Rinsed twice daily for 4 consecutive days. Abstinence from mechanical oral hygiene during use. 15-day washout before/after sequence.
Locations (1)
Hospital Odontològic Universitat de Barcelona
Barcelona, Catalonia, Spain