Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT07827391

Comparative Evaluation of Omega-3 and Resveratrol Supplementation in Periodontitis Patients

Sponsor: Izmir Katip Celebi University

View on ClinicalTrials.gov

Summary

This retrospective comparative study aims to evaluate the effects of resveratrol and omega-3 supplementation as adjuncts to non-surgical periodontal treatment on clinical periodontal parameters in patients with periodontitis. A total of 60 systemically healthy, non-smoking patients will be evaluated and categorized into three groups according to their recorded supplementation status: a resveratrol group receiving non-surgical periodontal treatment plus resveratrol supplementation (n=20), an omega-3 group receiving non-surgical periodontal treatment plus omega-3 supplementation (n=20), and a non-supplemented control group receiving non-surgical periodontal treatment alone (n=20). Periodontal outcomes will be assessed at baseline and at 1 and 3 months after non-surgical periodontal treatment using probing pocket depth, clinical attachment level, plaque index, gingival index, and bleeding on probing. The study aims to compare the clinical periodontal outcomes of the three groups and determine whether adjunctive resveratrol or omega-3 supplementation is associated with additional clinical benefits beyond non-surgical periodontal treatment alone.

Official title: A Retrospective Comparative Evaluation of the Effects of Adjunctive Omega-3 and Resveratrol Supplementation to Non-Surgical Periodontal Therapy on Clinical Periodontal Parameters in Systemically Healthy Patients With Periodontitis.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2025-01-01

Completion Date

2028-03-15

Last Updated

2026-09-18

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

trans-resveratrol

Trans-resveratrol supplementation at a dose of 250 mg twice daily (500 mg/day total) during non-surgical periodontal treatment.

DIETARY_SUPPLEMENT

Omega-3 (EPA+DHA)

Omega-3 fatty acid supplementation at a total daily dose of 1320 mg, including 640 mg EPA and 480 mg DHA, during non-surgical periodontal treatment.

DIETARY_SUPPLEMENT

No supplementation

Patients who underwent non-surgical periodontal treatment without receiving resveratrol or omega-3 fatty acid supplementation during the treatment period

Locations (1)

İzmir Katip Çelebi University, Faculty of Dentistry

Izmir, İzmir, Turkey (Türkiye)