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18F-FDG PET/CT for Diagnosis of Diabetic Foot Osteomyelitis
Sponsor: Jewish General Hospital
Summary
Diabetic foot osteomyelitis (DFO) is a bone infection of the foot that can occur in people with diabetes and may lead to serious complications, including amputation. Diagnosing DFO can be difficult. This prospective multicenter observational study will evaluate how accurately 18F-FDG PET/CT can diagnose DFO in patients who are already referred for this imaging test as part of their clinical care. The study will use current-generation digital PET/CT systems and standardized interpretation criteria. PET/CT findings will be compared with bone biopsy results when available, or with clinical and imaging findings obtained during at least 6 months of follow-up.
Official title: 18F-FDG PET/CT for Diagnosis of Diabetic Foot Osteomyelitis: A Prospective Multicenter Study of Diagnostic Accuracy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2026-11
Completion Date
2029-04
Last Updated
2026-09-18
Healthy Volunteers
No
Conditions
Interventions
18F-FDG PET/CT
18F-FDG PET/CT of the feet performed using current-generation digital PET/CT systems and a standardized acquisition protocol. PET/CT images will subsequently be evaluated using standardized interpretation criteria to determine diagnostic performance for diabetic foot osteomyelitis.
Locations (4)
UT Southwestern Medical Center
Dallas, Texas, United States
Hôpital du Sacré-Cœur de Montréal
Montreal, Canada
Jewish General Hospital
Montreal, Canada
McGill University Health Centre
Montreal, Canada