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Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway Ventilation
Sponsor: Korea University Guro Hospital
Summary
This prospective, randomized, double-blind study aims to evaluate the effect of different degrees of neuromuscular blockade on the performance of a video laryngeal mask airway (LMA) during general anesthesia. Participants will be randomly assigned to receive rocuronium at 0, 0.3, or 0.6 mg/kg, corresponding to 0, 1, or 2 times the ED95, respectively. The primary outcome is oropharyngeal leak pressure measured after LMA insertion. Secondary outcomes include LMA insertion conditions, insertion time and number of attempts, laryngeal view, respiratory parameters, and postoperative airway-related complications.
Official title: The Relationship Between the Degree of Neuromuscular Blockade and the Conditions of Laryngeal Mask Ventilation: A Prospective Randomized Double-Blind Study
Key Details
Gender
All
Age Range
20 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
96
Start Date
2026-09-07
Completion Date
2027-08-30
Last Updated
2026-09-18
Healthy Volunteers
No
Interventions
Normal Saline (Rocuronium 0 mg/kg)
Normal saline is administered intravenously as the control study drug before video LMA insertion.
Rocuronium 0.3 mg/kg
Rocuronium 0.3 mg/kg (1 × ED95) is administered intravenously before video LMA insertion.
Rocuronium 0.6 mg/kg
Rocuronium 0.6 mg/kg (2 × ED95) is administered intravenously before video LMA insertion.