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Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population
Sponsor: Tripler Army Medical Center
Summary
The primary objective of the protocol is to learn about how SAP P 11-4 (produced commercially as Curodont products) can be used in a military population to treat incipient dental caries, or developing cavities that are still structurally intact and not too deep and increase awareness of the improvement and availability of minimally invasive treatment options for cavities in a military population.
Official title: Can SAP P11-4 Increase The Radiopacity of Incipient Interproximal Carious Lesions on a Radiograph in a Military Population
Key Details
Gender
All
Age Range
18 Years - 74 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-09-30
Completion Date
2027-08
Last Updated
2026-09-21
Healthy Volunteers
No
Conditions
Interventions
0.05% Sodium Fluoride with Self-Assembling Peptides
Single topical application of Curodont Repair Fluoride Plus (containing 0.05% sodium fluoride and self-assembling P11-4 peptide technology) directly to identified non-cavitated interproximal early carious lesions (radiographic stages E1, E2, or D1) at baseline per manufacturer instructions. Participants receive standardized oral hygiene instruction (OHI) reinforcing brushing and flossing technique and frequency at baseline and at all recall appointments. Follow-up standardized bitewing radiographs are obtained at 1 week, 1 month, and 3 months with no real-time filters or enhancements to evaluate lesion density changes via pixel region-of-interest (ROI) analysis.
Locations (1)
Schofield Barracks Dental Clinic
Schofield Barracks, Hawaii, United States