Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
NOT YET RECRUITING
NCT07830862
NA

The Effect of a Postbiotic on Oral Health in Healthy Adults

Sponsor: The Archer-Daniels-Midland Company

View on ClinicalTrials.gov

Summary

The goal of this randomised, placebo-controlled trial is to determine the effect of a chewable postbiotic tablet on the oral health of male and female healthy adults under conditions of short term oral-neglect (a short, temporary period during which participants do not perform their usual oral hygiene practices, such as tooth brushing and flossing). The main questions the study aims to answer are: 1. Does postbiotic ingestion impact dental plaque accumulation, gingival (gum) inflammation, and periodontal health compared with placebo? 2. Does postbiotic ingestion alter the oral microbiome composition compared with placebo?

Official title: A Randomised, Triple-Blind, Placebo-Controlled, Parallel Study to Investigate the Effects of a Chewable Postbiotic Tablet on Oral Health in Healthy Adults

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

56

Start Date

2026-10-01

Completion Date

2027-06-01

Last Updated

2026-09-21

Healthy Volunteers

Yes

Conditions

Interventions

DIETARY_SUPPLEMENT

Postbiotic

1 tablet to be taken after brushing in the morning and 1 tablet to be taken after brushing in the evening for 6 weeks. Tablets should be chewed until fully dissolved. The active intervention provides 10mg of heat-treated postbiotic per day. The postbiotic is manufactured by heat treatment of a probiotic preparation equivalent to 3.0 × 10\^9 CFU.

DIETARY_SUPPLEMENT

Placebo

1 tablet to be taken after brushing in the morning and 1 tablet to be taken after brushing in the evening for 6 weeks. Tablets should be chewed until fully dissolved. The placebo tablet is matched to the active tablet in packaging, appearance, and taste.

Locations (1)

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Guelph, Ontario, Canada