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Childhood Obesity Risk Markers (MARIOBE)
Sponsor: University Hospital, Clermont-Ferrand
Summary
Metabolic diseases, including childhood obesity, represent a major public health challenge. Studies in mice have identified transcriptomic markers in adipose tissue capable of predicting a predisposition to obesity prior to any weight gain. The MARIOBE project aims to translate this approach to young children (≤ 4 years old) in order to identify individual vulnerability to obesity at an early stage.
Official title: Childhood Obesity Risk Markers
Key Details
Gender
All
Age Range
1 Day - 4 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2026-09
Completion Date
2036-09
Last Updated
2026-09-21
Healthy Volunteers
Yes
Conditions
Interventions
early transcriptomic markers
during a scheduled surgery before the age of 4 years, collection of a blood sample (2.5 mL in a PAXgene tube) and two adipose tissue fragments, each measuring 5 mm x 5 mm x 5 mm. tracking of weight and height curves from birth to age 6
Locations (1)
CHU de Clermont-Ferrand
Clermont-Ferrand, France