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NOT YET RECRUITING
NCT07831434

Postoperative Residual Neuromuscular Block and Passive Smoke Exposure in Pediatric Dental Patients

Sponsor: Istanbul University - Cerrahpasa

View on ClinicalTrials.gov

Summary

Postoperative residual neuromuscular block (PRNB) may persist despite apparent clinical recovery from neuromuscular blockade and may increase the risk of postoperative respiratory complications. Quantitative neuromuscular monitoring is therefore important for identifying incomplete neuromuscular recovery. This prospective, single-center observational cohort study aims to determine the incidence of PRNB in pediatric patients undergoing dental procedures under general anesthesia with rocuronium and to evaluate the association between passive smoke exposure and PRNB. Children aged 2-12 years will undergo quantitative neuromuscular assessment using the TOF-Watch SX after clinical extubation and admission to the post-anesthesia care unit (PACU). PRNB will be defined as a train-of-four (TOF) ratio \<0.9. The incidence of PRNB will be determined, and its association with passive smoke exposure and perioperative clinical variables will be evaluated.

Official title: Association Between Postoperative Residual Neuromuscular Block After Rocuronium Administration and Passive Smoke Exposure in Pediatric Patients Undergoing Dental Procedures

Key Details

Gender

All

Age Range

2 Years - 12 Years

Study Type

OBSERVATIONAL

Enrollment

55

Start Date

2026-09

Completion Date

2027-09

Last Updated

2026-09-21

Healthy Volunteers

No

Interventions

OTHER

Passive Smoke Exposure

Passive smoke exposure is defined based on parental or legal guardian report of the child's exposure to tobacco smoke in the household or other environments. No intervention is administered as part of the study

Locations (1)

Istanbul University-Cerrahpasa, Institute of Cardiology

Istanbul, Istanbul, Turkey (Türkiye)