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RECRUITING
NCT07831707

The Role of Visual Attention and Environmental Complexity in Real-world Mobility for People With Lower Limb Amputation

Sponsor: Virginia Commonwealth University

View on ClinicalTrials.gov

Summary

Despite high medical expenses (\>$500K/patient), mobility improvements achieved during rehabilitation for people with lower limb amputation (LLA) fail to translate into improved real-world outcomes. Even with advances in prosthesis technology enabling faster gait speed, greater walking endurance, and improved mobility confidence, people with LLA report persistent dissatisfaction with real-world mobility, limited ability to walk in the community, and difficulty achieving recommended physical activity levels. Real-world walking requires thinking and moving simultaneously (e.g., cognitive-motor dual-tasking), visually attending to the environment, and navigating varying terrain. In contrast, clinical mobility assessments are usually performed without additional visual or cognitive demands, in controlled environments, and on level surfaces. Current clinical tools used to assess ambulation progression during rehabilitation do not adequately assess these changes in people who have experienced LLA.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

30

Start Date

2025-10-25

Completion Date

2027-05-31

Last Updated

2026-09-21

Healthy Volunteers

No

Interventions

OTHER

Comprehensive assessment of walking patterns and functional mobility

Assessment of accelerometry: Daily duration (minutes) of sitting, standing, stepping, Daily step count, Daily walking bouts stepping cadence, Timed Up and Go and Two-minute Walk Test

OTHER

Comprehensive assessment of eye movements during walking

Comprehensive assessment of eye movements during walking including Target Fixation Time (seconds; %) and Number of fixations

OTHER

Questionnaire Assessments completed

The following assessments will be completed: World health organization disability assessment schedule 2.0 (WHODAS), and Activities Specific Balance Confidence Scale.

Locations (1)

Virginia Commonwealth University

Richmond, Virginia, United States