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Study on the Prevention of Weight Loss Through Physical Activity Among Nursing Home Residents
Sponsor: University Hospital, Toulouse
Summary
Appetite loss is frequent in institutionalized older adults. Physical activity is known for its benefits on appetite regulation but its effects in nursing home residents remain poorly investigated. This project will investigate the 6-month longitudinal relationships between daily physical activity time with appetite and bodyweight and how engaging in a 6-month regular exercise program can improve theses outcomes in older institutionalized older adults.
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
596
Start Date
2026-09-01
Completion Date
2028-09-01
Last Updated
2026-09-21
Healthy Volunteers
No
Conditions
Interventions
Physical activity
The participants will partake in physical activity sessions twice a week for about 45-60 minutes each which will consist of exercises designed to improve mobility, motor skills, balance, strength and muscular endurance, as well as the cardiorespiratory system. All exercises will be tailored to each person's abilities and can be performed while sitting or standing.
Appetite assessment
The appetite will be evaluated by a self-assessment questionnaire SNAQ.
Food intake assessment
It will be assessed by the healthcare team of the patient at baseline and at the end of the study.
Assessment of the efficiency
It will be evaluated by a self-assessment questionnaire EQ-5D-5L.
Blood test at baseline
A blood test will be done at the beginning of the study to evaluate the blood concentrations of leptin, insulin and GDF-15.
Blood test at the end of the study
It will be done at the end of the study (month 6) to evaluate the changes in blood concentrations of leptin, insulin and GDF-15.
Functional capacities assessment
The functional capacities will be assessed by : * Mini-Mental State Examination (MMSE) for cognition * Mini Nutritional Assessment (MNA) short form for nutrition * Whisper test for hearing * step-1 ICOPE question for vision * Short Physical Performance Battery (SPPB) and grip strength for mobility * Montgomery-Åsberg Depression Rating Scale (MADRS) and PHQ-2 for mood
weight measurment
the weight will be measured every month (kilogramm).
Locations (1)
University Hospital
Toulouse, France