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NCT07832019

Placenta-Cervical Interface Angle for Predicting Placenta Accreta Spectrum Severity

Sponsor: Necmettin Erbakan University

View on ClinicalTrials.gov

Summary

Placenta accreta spectrum (PAS) is associated with substantial maternal and neonatal morbidity, and accurate antenatal prediction of its severity remains challenging. Although several sonographic markers exist, most are subjective and operator-dependent, and few predict surgical complexity or adverse perinatal outcomes. This prospective observational cohort study evaluates the Placenta-Cervical Interface Angle (PCIA), a novel geometric transvaginal ultrasound marker, defined as the angle between the longitudinal axis of the cervical canal and the tangent line drawn to the lower placental edge. The study assesses the predictive performance of the PCIA for severe PAS and its association with intraoperative morbidity and adverse perinatal outcomes.

Official title: Placenta-Cervical Interface Angle: A Novel Sonographic Marker for Predicting Placenta Accreta Spectrum Severity and Perinatal Outcomes

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-09-15

Completion Date

2027-05-15

Last Updated

2026-09-21

Healthy Volunteers

No

Interventions

PROCEDURE

Pregnant women at risk of PAS

Transvaginal ultrasonography performed in the sagittal plane to measure the Placenta-Cervical Interface Angle (PCIA), defined as the angle between the longitudinal axis of the cervical canal and the tangent to the lower placental edge, together with assessment of classic sonographic PAS markers.

Locations (1)

Necmettin Erbakan University, Faculty of Medicine, Perinatology Clinic

Konya, Konya, Turkey (Türkiye)