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30-Second Versus Pulsation-Based Delayed Cord Clamping in Term Newborns
Sponsor: Tarsus University
Summary
This randomized controlled trial aims to compare the effects of 30-second cord clamping and pulsation-based delayed cord clamping on neonatal metabolic adaptation in term newborns delivered vaginally. Eligible mother-newborn pairs will be randomly assigned in a 1:1 ratio to either 30-second cord clamping or pulsation-based delayed cord clamping. In the intervention group, the umbilical cord will be clamped after spontaneous cessation of cord pulsation, whereas in the control group, the cord will be clamped 30 seconds after birth. The primary outcome is umbilical arterial lactate level. Secondary outcomes include umbilical arterial pH, pCO2, pO2, HCO3-, base deficit, 1- and 5-minute Apgar scores, and maternal postpartum blood loss.
Official title: Effects of 30-Second and Pulsation-Based Delayed Cord Clamping on Neonatal Metabolic Adaptation: A Randomized Controlled Trial.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
122
Start Date
2026-10
Completion Date
2027-03
Last Updated
2026-09-22
Healthy Volunteers
Yes
Conditions
Interventions
Pulsation-Based Delayed Cord Clamping
The umbilical cord will remain intact after birth until cord pulsation spontaneously and completely ceases. During this period, the newborn will be placed on the mother's abdomen for skin-to-skin contact and routine thermal protection. After complete cessation of cord pulsation, the umbilical cord will be clamped and cut. The actual time from birth to cord clamping will be recorded in seconds.
30-Second Cord Clamping
The umbilical cord will be clamped and cut 30 seconds after birth. During this period, the newborn will be placed on the mother's abdomen for skin-to-skin contact and routine thermal protection. The actual time from birth to cord clamping will be recorded in seconds.
Locations (1)
Seyhan State Hospital MARSA Additional Service Building
Adana, Turkey (Türkiye)