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RECRUITING
NCT07833085
NA

CAIX-targeted PET/CT in Solid Tumors

Sponsor: Zhongnan Hospital

View on ClinicalTrials.gov

Summary

Tumor hypoxic microenvironment plays an important role in the initiation and progression of solid tumors, as well as tumor invasion, metastasis, and treatment resistance. Carbonic anhydrase IX (CAIX), as a crucial downstream molecule regulated by hypoxia-inducible factor-1 (HIF-1), is highly expressed in various solid tumors and is closely associated with tumor invasiveness, treatment response, and prognosis; thus, it represents an ideal target for tumor diagnosis and therapy. This study aims to explore the diagnostic value of CAIX-targeted PET/CT imaging in various solid tumors, as well as the correlation between tumor uptake and tissue CAIX expression.

Official title: Carbonic Anhydrase IX-targeted PET/CT Imaging for Detecting Solid Tumors

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-09-21

Completion Date

2031-12-31

Last Updated

2026-10-13

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

68Ga-CAIX

The subjects receive a PET/CT scan 30-60 minutes after intravenous administration of 68Ga-CAIX

Locations (1)

Zhongnan hospital of Wuhan University

Wuhan, Hubei, China