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Senocohort: Identification of Predictive Biomarkers in Breast Cancer Treatment
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Breast cancer is a heterogeneous disease with multiple molecular subtypes, each requiring tailored therapeutic strategies. The recent introduction of targeted therapies, immunotherapies, and antibody-drug conjugates has expanded treatment options, yet their efficacy varies depending on tumor subtype. This non-interventional study aims to identify novel predictive biomarkers of response or resistance to these emerging therapies. The Senocohort study will prospectively collect clinical, biological, imaging, and organoid-derived data from breast cancer patients, with a focus on hormone receptor-negative tumors. The ultimate goal is to improve precision medicine strategies and patient stratification
Official title: Recherche de Biomarqueurs prédictifs de réponse ou de résistance Dans Les Traitements Des Cancers du Sein
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2026-10-01
Completion Date
2041-10-01
Last Updated
2026-09-22
Healthy Volunteers
No
Interventions
Patients follow-up
Blood sampling, residual tissue material collection and clinical data collection