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Feasibility of Multi-cancer Early Detection Test in Screening Population (NQMD-CS)
Sponsor: Fifth Affiliated Hospital of Guangzhou Medical University
Summary
This is a prospective, multicenter screening cohort study designed to evaluate the feasibility of a blood-based multi-cancer early detection (MCED) test in an asymptomatic screening population. Eligible participants will undergo blood-based MCED testing, standard cancer screening as appropriate, and 1-year active follow-up. Participants with positive MCED results or highly suspicious findings from standard screening will undergo diagnostic evaluation to determine cancer status, enabling a more accurate assessment of the test's clinical performance.
Official title: NQMD-CS: A Prospective Interventional Study to Evaluate the Feasibility of a Blood-Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population
Key Details
Gender
All
Age Range
40 Years - 74 Years
Study Type
INTERVENTIONAL
Enrollment
1250
Start Date
2025-07-02
Completion Date
2026-10
Last Updated
2026-09-22
Healthy Volunteers
Yes
Interventions
MCED
A cfDNA methylation-based early cancer detection model that provides a binary positive/negative result and predicts the tissue of origin when a cancer-associated signal is detected.
Locations (2)
The Fifth Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
Huidong People's Hospital
Huizhou, Guangdong, China