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Effect of Bone Graft Material ON Peri-Implant Phenotype .
Sponsor: Al-Mustansiriyah University
Summary
This prospective three-arm controlled interventional clinical study evaluates the effects of NanoBone alone and NanoBone combined with platelet-rich fibrin (PRF) on peri-implant hard and soft tissue phenotype after dental implant placement. Thirty-nine adult participants requiring dental implant therapy will be assigned to three groups of 13 using a repeating sequential 1-2-3 allocation sequence: implant placement alone (control), implant placement with NanoBone, or implant placement with NanoBone and PRF/CGF membrane. Clinical and radiographic outcomes will be assessed at baseline, immediately after surgery, 8 weeks after surgery, and 4 months after surgery, with an early postoperative assessment of pain, swelling, medication use, and wound healing.
Official title: Evaluation of the Effect of Bone Graft Materials on Peri-Implant Phenotype: A Prospective Three-Arm Controlled Interventional Clinical Study
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
39
Start Date
2026-07-02
Completion Date
2026-09-01
Last Updated
2026-09-23
Healthy Volunteers
Yes
Conditions
Interventions
Dental implant placement
Dental implant placement without adding bone graft material or bone substitute at the implant site, according to the study protocol.
NanoBone
Application of NanoBone at the implant site during dental implant placement.
NanoBone sticky bone plus CGF/PRF membrane
Application of NanoBone sticky bone combined with a CGF/PRF membrane at the implant site during dental implant placement.
Locations (1)
Mustansiriyah University - College of Dentistry
Baghdad, Iraq