Clinical Research Directory
Browse clinical research sites, groups, and studies.
Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial
Sponsor: Yale University
Summary
Cigarette smoking is an important cause of illness and death among persons with HIV (PWH). This project will study the impact of adding contingency management (use of financial rewards) to receiving medications and counseling on promoting smoking abstinence and other health outcomes among PWH. As treatments will be provided by clinical pharmacists and other team members in HIV clinics, factors relevant for implementing this model to inform real-world practice will also be evaluated.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
794
Start Date
2027-09-30
Completion Date
2031-09-30
Last Updated
2026-09-23
Healthy Volunteers
No
Interventions
nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion
Clinical pharmacist prescribed MTUD, based on participant choice: nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion. Participants on nicotine replacement may choose both a long acting (patch) and short acting (gum, lozenge) option to use at the same time.
Multi-target Contingency Management
Participants will earn prizes for progress towards tobacco abstinence, achieving tobacco abstinence, and progress in improving HIV and other related health conditions.
Teamlet booster
Participants will receive a booster call by a teamlet member after MTUD is prescribed to address any MTUD access issues and answer MTUD related questions.
Locations (5)
Bridgeport Hospital Primary Care Center Infectious Disease Clinic
Bridgeport, Connecticut, United States
Yale Center for Infectious Diseases
New Haven, Connecticut, United States
Center for Comprehensive Care at Jersey City Medical Center
Jersey City, New Jersey, United States
Center for Comprehensive Care at St. Joseph's Health
Paterson, New Jersey, United States
Special Treatment And Research (STAR) at SUNY Downstate
Brooklyn, New York, United States