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ACTIVE NOT RECRUITING
NCT07836634
NA

Effects of Nattokinase Supplementation on Strength Recovery and Muscle Damage Biomarkers Following Exercise-Induced Muscle Injury: A Pilot Study

Sponsor: National Taiwan Sport University

View on ClinicalTrials.gov

Summary

This pilot study aims to investigate whether 4 weeks of nattokinase supplementation (2,000 FU/day) affects recovery following exercise-induced muscle damage in healthy adult men. Approximately 12 to 16 participants aged 18 to 40 years will receive either nattokinase or a matching placebo during the supplementation period. After supplementation, participants will complete an exercise protocol designed to induce temporary muscle damage. Recovery will be evaluated using measures of muscle strength and exercise performance, muscle soreness, blood lactate, muscle oxygenation, and blood biomarkers related to muscle damage, inflammation, and oxidative stress. Measurements will be performed before and after the exercise-induced muscle damage protocol, including follow-up assessments during the recovery period. The study is intended to provide preliminary information on the potential effects of nattokinase supplementation on muscle recovery after strenuous exercise.

Key Details

Gender

MALE

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

14

Start Date

2026-09-03

Completion Date

2026-10-08

Last Updated

2026-09-23

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Nattokinase

Participants will consume one capsule of nattokinase orally once daily, providing 2,000 FU/day, for 28 days.

DIETARY_SUPPLEMENT

Placebo

Participants will consume one matching placebo capsule orally once daily for 28 days. The placebo is matched in appearance and flavor to the nattokinase supplement.

Locations (1)

Graduate Institute of Sports Science, National Taiwan Sport University

Taoyuan, Taiwan, Taiwan