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Blood Flow Restriction Training in Knee Arthropathy
Sponsor: Yuxiu Ji
Summary
Arthrogenic muscle inhibition (AMI) is the key neurophysiological cause of impeding quadriceps activation following anterior cruciate ligament reconstruction (ACLR). Blood flow restriction training (BFRT) may induce neuroplasticity whereas the neurophysiological responses remain uncertain. In this study, we aimed to explore the effects of constant pressure blood flow restriction training (CP-BFRT) on neurophysiological responses and physical function. Patients will receive the same standardized progressive physical rehabilitation for 2 weeks after the surgery and then start the BRFT or sham BRFT intervention for the following 12 weeks.
Official title: Effects of Blood Flow Restriction Training on Lower Limb Muscle Strength and Atrophy in Patients With Knee Arthropathy: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2026-09-01
Completion Date
2026-12-31
Last Updated
2026-09-23
Healthy Volunteers
No
Interventions
Blood flow restriction training with 60%-80% occlusion
A personalized constant-pressure system served as the active BFRT unit, with restrictive pressure set at 60%-80% of limb arterial occlusion pressure; it auto-inflates to maintain constant pressure and automatically monitors, assesses, and adjusts pressure during training.
Standard postoperative knee rehabilitation with sham BFRT
Standard postoperative rehabilitation protocol after knee arthroscopic surgery, without blood flow restriction training. The rehabilitation program includes range of motion exercises, muscle strength training, balance training and functional activity training, with the same schedule, frequency and duration as the experimental group.
Locations (1)
The Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, China