Clinical Research Directory

Inclusion Criteria: * Age between 18 and 90 years old * ASA status I to III inclusively * Planned lower body surgery under spinal anesthesia with chloroprocaine * Signed informed consent form Exclusion Criteria: * Contraindication to spinal anesthesia: infection at the puncture site, congenital or acquired coagulopathy * Preexisting neuropathy or nerve block that could interfere with study assessments * Allergy or hypersensitivity to local anesthetics, dexamethasone, or other medications used in the study * Preoperative use of corticosteroids * Patient refusal * Inability to consent * Language barrier, psychiatric, physical, or mental condition making sensory and motor blocks assessment impossible despite prior instruction * Administration of any intrathecal adjuvant (fentanyl, morphine, clonidine, dexmedetomidine, epinephrine, or others) along with chloroprocaine * Perioperative intravenous dexmedetomidine administration * Conversion to general anesthesia * Impossible post-anesthesia care unit assessment: patient still intubated / transfer to intensive care unit, research team constraints, or other reasons * Assessment in the recovery room impossible: medical condition (shock, delirium, major agitation, altered state of consciousness, or other), transfer to the intensive care unit, research team constraints, or other