Clinical Research Directory

Inclusion Criteria: 1. Age 18 years or older. 2. Diagnosis of head and neck cancer (AJCC stages I-IV). 3. Completed curative-intent primary treatment, including surgery, radiation, chemotherapy, or combination treatment, within the past 1 to 3 months. 4. Clearance to engage in moderate-intensity exercise based on the American College of Sports Medicine (ACSM) Preparticipation Screening Guidelines. 5. Willingness and ability to participate in both in-person and/or virtual supervised exercise sessions. 6. Willingness to adhere to the supplementation regimen throughout the study. 7. English-speaking and able to understand study instructions and complete questionnaires. 8. Access to internet for remotely supervised exercise sessions. 9. Availability for the full 10-week intervention and post-intervention assessments. Exclusion Criteria: 1. Current participation in structured resistance training 2 or more days per week within the past 6 months. 2. Cognitive, psychiatric, or neurologic conditions that would impair ability to consent or adhere to study procedures. 3. Pre-existing renal impairment. 4. Current use of creatine supplements, defined as consistently taking creatine more than 2 days per week for the past 6 months.