Clinical Research Directory
Browse clinical research sites, groups, and studies.
Intraoperative Ketamine Versus Lidocaine Infusion on Postoperative Cognitive Dysfunction in Patients Undergoing Hip Surgery
Sponsor: Tanta University
Summary
This study aims to compare effects of ketamine versus lidocaine on postoperative cognitive dysfunction in geriatric patient undergoing hip surgery.
Official title: Effect of Intraoperative Ketamine Versus Lidocaine Infusion on Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Hip Surgery
Key Details
Gender
All
Age Range
66 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-03-30
Completion Date
2026-03-30
Last Updated
2026-09-24
Healthy Volunteers
No
Interventions
Group Ketamine
Patients will receive ketamine as a bolus (0.5 mg/kg) after induction of spinal anesthesia, followed by a continuous infusion (0.2 mg/kg. h) until the end of surgery.
Group Lidocaine
Patients will receive lidocaine as a bolus (1.5 mg/kg) after induction of spinal anesthesia, followed by a continuous infusion (2 mg/kg. h) until the end of surgery
Group Placebo
Patients will receive placebo (saline) and administered in equal volumes and in the same manner as a control group.
Locations (1)
Tanta University
Tanta, Egypt