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ENROLLING BY INVITATION
NCT07839195
PHASE2

Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis

Sponsor: Siriraj Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare the incidence of post-neurotomy neuritis (PNN) in adult patients undergoing radiofrequency neurotomy (RFN) for spine facet and sacroiliac joint pain, comparing those who receive a local corticosteroid injection after the procedure with those who do not. Participants are randomly assigned to receive either local anesthetic with dexamethasone or local anesthetic alone at the treatment sites. Pain scores, functional disability, and adverse events are evaluated before the procedure and at 4 weeks follow-up.

Official title: Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

126

Start Date

2026-10

Completion Date

2028-10

Last Updated

2026-09-24

Healthy Volunteers

Yes

Interventions

DRUG

Dexamethasone

Post-radiofrequency neurotomy (RFN) local injection consisting of dexamethasone mixed with 0.5% bupivacaine (approximately 1.5 mg/mL/level of dexamethasone). A total volume of 1 mL of the prepared solution is administered at each lesion site via the RF cannula.

DRUG

Normal Saline

In the non-steroid group, same 0.5% bupivacaine volume was diluted with normal saline in same volume to dexamethasone of steroid group for injectate volume corresponding to the number of lesion sites after complete radiofrequency neurotomy

Locations (1)

Siriraj pain clinic, Department of Anesthesiology, Faculty of Medicine Siriraj hospital

Bangkok, Thailand