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Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis
Sponsor: Siriraj Hospital
Summary
The purpose of this study is to compare the incidence of post-neurotomy neuritis (PNN) in adult patients undergoing radiofrequency neurotomy (RFN) for spine facet and sacroiliac joint pain, comparing those who receive a local corticosteroid injection after the procedure with those who do not. Participants are randomly assigned to receive either local anesthetic with dexamethasone or local anesthetic alone at the treatment sites. Pain scores, functional disability, and adverse events are evaluated before the procedure and at 4 weeks follow-up.
Official title: Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
126
Start Date
2026-10
Completion Date
2028-10
Last Updated
2026-09-24
Healthy Volunteers
Yes
Conditions
Interventions
Dexamethasone
Post-radiofrequency neurotomy (RFN) local injection consisting of dexamethasone mixed with 0.5% bupivacaine (approximately 1.5 mg/mL/level of dexamethasone). A total volume of 1 mL of the prepared solution is administered at each lesion site via the RF cannula.
Normal Saline
In the non-steroid group, same 0.5% bupivacaine volume was diluted with normal saline in same volume to dexamethasone of steroid group for injectate volume corresponding to the number of lesion sites after complete radiofrequency neurotomy
Locations (1)
Siriraj pain clinic, Department of Anesthesiology, Faculty of Medicine Siriraj hospital
Bangkok, Thailand