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Application Study of Individualized Mechanical Power Titration Strategy Based on PiCCO (Pulse Index Continuous Cardiac Output) Monitoring Parameters in ARDS Patients
Sponsor: Xiamen Hospital of Traditional Chinese Medicine
Summary
Based on PiCCO combined with MP, the optimal mechanical power setting of the ventilator for ARDS patients in normal supine/prone position is determined to reduce the damage to lung function during mechanical ventilation. By detecting peripheral serum NLRP3 and related inflammatory markers in ARDS patients, the relationship between NLRP3 and lung injury caused by mechanical ventilation was studied.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
130
Start Date
2025-11-04
Completion Date
2028-09-30
Last Updated
2026-09-24
Healthy Volunteers
No
Conditions
Interventions
Prone position ventilation
Judgement of Prone Position Therapy Based on Oxygenation Index
Locations (1)
Xiamen Hospital of Traditional Chinese Medicine
Xiamen, Fujian, China