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NCT07839858

A Study of Real-world Use and Effectiveness of Cytoreductive Strategies for the Treatment of Second-line Polycythemia Vera in France

Sponsor: Novartis Pharmaceuticals

View on ClinicalTrials.gov

Summary

The aim of this study was to assess which cytoreductive treatments are currently administered in standard practice as second-line therapy to patients with polycythemia vera (PV) in France and to find out the reasons physicians switch treatments. In addition, the research aimed to describe real-world effectiveness of second-line cytoreductive therapies and the occurrence of adverse events of special interest. Study data were collected from the medical charts of patients who initiated a second-line cytoreductive agent for the treatment of PV and received their first dose between 1 Jan 2022 and 31 Dec 2023.

Official title: Real-world Use and Effectiveness of Cytoreductive Strategies for the Treatment of Second-line Polycythemia Vera: A Multicenter, Retrospective, Non-interventional Study in France

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

237

Start Date

2025-03-13

Completion Date

2025-10-14

Last Updated

2026-09-24

Healthy Volunteers

No

Locations (51)

Novartis Investigative Site

Bayonne, Bayonne Cedex, France

Novartis Investigative Site

Saint Priest Jarez, Pays de la Loire Region, France

Novartis Investigative Site

Aix-en-Provence, France

Novartis Investigative Site

Amiens, France

Novartis Investigative Site

Angers, France

Novartis Investigative Site

Antony, France

Novartis Investigative Site

Arras, France

Novartis Investigative Site

Aurillac, France

Novartis Investigative Site

Avignon, France

Novartis Investigative Site

Béziers, France

Novartis Investigative Site

Bordeaux, France

Novartis Investigative Site

Brest, France

Novartis Investigative Site

Cesson-Sévigné, France

Novartis Investigative Site

Challes-les-Eaux, France

Novartis Investigative Site

Chambéry, France

Novartis Investigative Site

Clermont-Ferrand, France

Novartis Investigative Site

Corbeil-Essonnes, France

Novartis Investigative Site

Dunkirk, France

Novartis Investigative Site

Essey-lès-Nancy, France

Novartis Investigative Site

Grenoble, France

Novartis Investigative Site

Le Bouscat, France

Novartis Investigative Site

Le Chesnay, France

Novartis Investigative Site

Le Coudray, France

Novartis Investigative Site

Le Kremlin-Bicêtre, France

Novartis Investigative Site

Le Mans, France

Novartis Investigative Site

Libourne, France

Novartis Investigative Site

Lille, France

Novartis Investigative Site

Lyon, France

Novartis Investigative Site

Marseille, France

Novartis Investigative Site

Montpellier, France

Novartis Investigative Site

Morlaix Cdex, France

Novartis Investigative Site

Nantes, France

Novartis Investigative Site

Nîmes, France

Novartis Investigative Site

Orléans, France

Novartis Investigative Site

Paris, France

Novartis Investigative Site

Paris, France

Novartis Investigative Site

Paris, France

Novartis Investigative Site

Paris, France

Novartis Investigative Site

Perpignan, France

Novartis Investigative Site

Pessac, France

Novartis Investigative Site

Pierre-Bénite, France

Novartis Investigative Site

Poitiers, France

Novartis Investigative Site

Quimper, France

Novartis Investigative Site

Rennescedex9, France

Novartis Investigative Site

Rochefort, France

Novartis Investigative Site

Roubaix, France

Novartis Investigative Site

Saint-Brieuc, France

Novartis Investigative Site

St-Malo, France

Novartis Investigative Site

Strasbourg, France

Novartis Investigative Site

Trévenans, France

Novartis Investigative Site

Troyes, France