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A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
Sponsor: Verve Therapeutics, Inc.
Summary
The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.
Official title: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of VERVE-102, a One-Time Dose Gene Editing Medicine, in Adults With or at High Risk for Atherosclerotic Cardiovascular Disease (ASCVD) Who Require Additional Low-Density Lipoprotein-Cholesterol (LDL-C) Lowering
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
175
Start Date
2026-10
Completion Date
2030-03
Last Updated
2026-09-24
Healthy Volunteers
No
Interventions
VERVE-102
Administered IV
Placebo
Administered IV
Locations (1)
Epic Medical Research
DeSoto, Texas, United States