Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT07840131
NA

Anti-microbial Effect of Acacia Arabica Extract on Gingival and Periodontal Health of Dental Patients

Sponsor: Umm Al-Qura University

View on ClinicalTrials.gov

Summary

This randomized clinical pilot study evaluated the short-term effects of Acacia arabica mouth rinse and paste as adjuncts to conventional oral hygiene in adults with plaque-induced gingivitis. Thirty systemically healthy participants aged 18-42 years were randomly allocated into three groups: a control group receiving conventional oral hygiene measures, an Acacia arabica mouth rinse group, and an Acacia arabica paste group. All participants received professional plaque removal and standardized oral hygiene instructions at baseline. Participants in the intervention groups additionally used either the Acacia arabica mouth rinse or paste twice daily for four weeks. Clinical assessments were performed at baseline, 2 weeks, and 4 weeks. The study evaluated changes in plaque index, gingival index, bleeding on probing, and salivary pH. The study aimed to determine whether Acacia arabica formulations could provide additional short-term benefits in plaque and gingival inflammation control compared with conventional oral hygiene measures alone.

Official title: Short-term Effects of Acacia Arabica Mouth Rinse and Paste on Plaque-induced Gingivitis

Key Details

Gender

All

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-01-01

Completion Date

2025-12-30

Last Updated

2026-09-24

Healthy Volunteers

No

Interventions

OTHER

Acacia arabica Mouth Rinse

the rinse as 1 g extract/10 mL distilled water

OTHER

acacia arabica paste

a pea-sized amount of Acacia arabica paste (Gumtone® gel)

Locations (1)

Umm AlQuar University Dental Hospital

Mecca, Saudi Arabia