Clinical Research Directory
Browse clinical research sites, groups, and studies.
Anti-microbial Effect of Acacia Arabica Extract on Gingival and Periodontal Health of Dental Patients
Sponsor: Umm Al-Qura University
Summary
This randomized clinical pilot study evaluated the short-term effects of Acacia arabica mouth rinse and paste as adjuncts to conventional oral hygiene in adults with plaque-induced gingivitis. Thirty systemically healthy participants aged 18-42 years were randomly allocated into three groups: a control group receiving conventional oral hygiene measures, an Acacia arabica mouth rinse group, and an Acacia arabica paste group. All participants received professional plaque removal and standardized oral hygiene instructions at baseline. Participants in the intervention groups additionally used either the Acacia arabica mouth rinse or paste twice daily for four weeks. Clinical assessments were performed at baseline, 2 weeks, and 4 weeks. The study evaluated changes in plaque index, gingival index, bleeding on probing, and salivary pH. The study aimed to determine whether Acacia arabica formulations could provide additional short-term benefits in plaque and gingival inflammation control compared with conventional oral hygiene measures alone.
Official title: Short-term Effects of Acacia Arabica Mouth Rinse and Paste on Plaque-induced Gingivitis
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-01-01
Completion Date
2025-12-30
Last Updated
2026-09-24
Healthy Volunteers
No
Conditions
Interventions
Acacia arabica Mouth Rinse
the rinse as 1 g extract/10 mL distilled water
acacia arabica paste
a pea-sized amount of Acacia arabica paste (Gumtone® gel)
Locations (1)
Umm AlQuar University Dental Hospital
Mecca, Saudi Arabia