Clinical Research Directory

Inclusion Criteria: * Adults aged 18 years or older * Residents of the United States * New Ash users with active accounts at the time of recruitment * English-speaking * Able to provide informed consent * At screening: PHQ-9 total score \>= 10 (indicating at least moderate depressive symptoms) * During onboarding, indicated that they are willing to share their data and are interested in being contacted about and participating in research Exclusion Criteria: * Currently engaged in individual therapy or counseling * ASRM total score \>= 6 at screening (positive screen for mania) * PRIME-5 positive at screening, defined as \>= 1 item rated 6 (Definitely Agree) OR \>= 3 items rated 5 (Somewhat Agree) (positive screen for psychosis-spectrum symptoms) * Self-reported heavy episodic drinking at a frequency of weekly or more often on the NIAAA single-item alcohol screen (past 12 months) * Self-reported nonmedical drug use at a frequency of weekly or more often on the NIDA single-item substance use screen (past 12 months) * Any change to psychiatric medications in the 6 weeks prior to screening (any response other than "No changes to my meds in the past 6 weeks") * Currently in inpatient, residential, intensive outpatient (IOP), or partial hospitalization (PHP) mental health treatment * Suicidality - PHQ-9 item 9 score of 3 Special Populations: No minors are enrolled. Adults unable to consent are not enrolled. Pregnant women are not excluded. Prisoners are not targeted; the recruitment channel (an in-app prompt to consenting adult Ash users) is not anticipated to reach incarcerated populations, and prisoners will not be knowingly enrolled.