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Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain Injury
Sponsor: Samuel Cramer
Summary
This is a preliminary, prospective interventional feasibility study to investigate the use of cortical reverberation (CR) monitoring in patients with traumatic brain injury (TBI) requiring a clinically indicated external ventricular drain (EVD) placement.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2026-05-01
Completion Date
2028-01-30
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Interventions
A multi-contact depth electrode
Placement of a multi-contact depth electrode through the same burr hole created with a twist drill for clinically indicated EVD placement in TBI patients. The electrode will be positioned adjacent to the EVD catheter and connected to a stimulator/recording system to deliver biphasic, charge- balanced pulses (1-6 mA, 60-1000 µs) between adjacent contacts less than or equal to once every 3 seconds (0.33 Hz) while recording evoked cortical reverberation responses.
Locations (1)
Hennepin Healthcare Research Institute
Minneapolis, Minnesota, United States